2022 (Holiday)

Stranger in a Strange Land

Robert A. Heinlein

Valentine Michael Smith is a human being raised on Mars, newly returned to Earth. Among his people for the first time, he struggles to understand the social mores and prejudices of human nature that are so alien to him, while teaching them his own fundamental beliefs in grokking, watersharing, and love.

Surrender: 40 Songs, One Story

Bono

Bono--artist, activist, and the lead singer of Irish rock band U2--has written a memoir: honest and irreverent, intimate and profound, Surrender is the story of the remarkable life he's lived, the challenges he's faced, and the friends and family who have shaped and sustained him.

"When I started to write this book, I was hoping to draw in detail what I'd previously only sketched in songs. The people, places, and possibilities in my life. Surrender is a word freighted with meaning for me. Growing up in Ireland in the seventies with my fists up (musically speaking), it was not a natural concept. A word I only circled until I gathered my thoughts for the book. I am still grappling with this most humbling of commands. In the band, in my marriage, in my faith, in my life as an activist. Surrender is the story of one pilgrim's lack of progress ... With a fair amount of fun along the way." --Bono

As one of the music world's most iconic artists and the cofounder of the organizations ONE and (RED), Bono's career has been written about extensively. But in Surrender, it's Bono who picks up the pen, writing for the first time about his remarkable life and those he has shared it with. In his unique voice, Bono takes us from his early days growing up in Dublin, including the sudden loss of his mother when he was fourteen, to U2's unlikely journey to become one of the world's most influential rock bands, to his more than twenty years of activism dedicated to the fight against AIDS and extreme poverty. Writing with candor, self-reflection, and humor, Bono opens the aperture on his life--and the family, friends, and faith that have sustained, challenged, and shaped him.

Surrender's subtitle, 40 Songs, One Story, is a nod to the book's forty chapters, which are each named after a U2 song. Bono has also created forty original drawings for Surrender, which appear throughout the book.

Team of Rivals: The Political Genius of Abraham Lincoln

Doris Kearns Goodwin

Winner of the Lincoln Prize

Acclaimed historian Doris Kearns Goodwin illuminates Lincoln's political genius in this highly original work, as the one-term congressman and prairie lawyer rises from obscurity to prevail over three gifted rivals of national reputation to become president.

On May 18, 1860, William H. Seward, Salmon P. Chase, Edward Bates, and Abraham Lincoln waited in their hometowns for the results from the Republican National Convention in Chicago. When Lincoln emerged as the victor, his rivals were dismayed and angry.

Throughout the turbulent 1850s, each had energetically sought the presidency as the conflict over slavery was leading inexorably to secession and civil war. That Lincoln succeeded, Goodwin demonstrates, was the result of a character that had been forged by experiences that raised him above his more privileged and accomplished rivals. He won because he possessed an extraordinary ability to put himself in the place of other men, to experience what they were feeling, to understand their motives and desires.

It was this capacity that enabled Lincoln as president to bring his disgruntled opponents together, create the most unusual cabinet in history, and marshal their talents to the task of preserving the Union and winning the war.

We view the long, horrifying struggle from the vantage of the White House as Lincoln copes with incompetent generals, hostile congressmen, and his raucous cabinet. He overcomes these obstacles by winning the respect of his former competitors, and in the case of Seward, finds a loyal and crucial friend to see him through.

This brilliant multiple biography is centered on Lincoln's mastery of men and how it shaped the most significant presidency in the nation's history.

The Inner Game of Tennis: The Classic Guide to the Mental Side of Peak Performance

W. Timothy Gallwey

The timeless guide to achieving the state of “relaxed concentration” that’s not only the key to peak performance in tennis but the secret to success in life itself—part of the bestselling Inner Game series, with more than one million copies sold!

“Groundbreaking . . . the best guide to getting out of your own way . . . Its profound advice applies to many other parts of life.”—Bill Gates, GatesNotes (“Five of My All-Time Favorite Books”)
 
This phenomenally successful guide to mastering the game from the inside out has become a touchstone for hundreds of thousands of people. Billie Jean King has called the book her tennis bible; Al Gore has used it to focus his campaign staff; and Itzhak Perlman has recommended it to young violinists. Based on W. Timothy Gallwey’s profound realization that the key to success doesn’t lie in holding the racket just right, or positioning the feet perfectly, but rather in keeping the mind uncluttered, this transformative book gives you the tools to unlock the potential that you’ve possessed all along.
 
“The Inner Game” is the one played within the mind of the player, against the hurdles of self-doubt, nervousness, and lapses in concentration. Gallwey shows us how to overcome these obstacles by trusting the intuitive wisdom of our bodies and achieving a state of “relaxed concentration.” With chapters devoted to trusting the self and changing habits, it is no surprise then, that Gallwey’s method has had an impact far beyond the confines of the tennis court.
 
Whether you want to play music, write a novel, get ahead at work, or simply unwind after a stressful day, Gallwey shows you how to tap into your utmost potential. No matter your goals, The Inner Game of Tennis gives you the definitive framework for long-term success.

Mendeleyev's Dream

Paul Strathern

The acclaimed author of Under the Harrow and A Double Life returns with her most thrilling novel to date: the story of two sisters who become entangled with the IRA.

A producer at the Belfast bureau of the BBC, Tessa is at work one day when the news of another raid comes on the air. The IRA may have gone underground after the Good Friday agreement, but they never really went away, and lately, bomb threats, arms drops, and helicopters floating ominously over the city have become features of everyday life. As the anchor requests the public's help in locating those responsible for this latest raid - a robbery at a gas station - Tessa's sister appears on the screen. Tessa watches in shock as Marian pulls a black mask over her face.

The police believe Marian has joined the IRA, but Tessa knows this is impossible. They were raised to oppose Republicanism, and the violence enacted in its name. They've attended peace vigils together. And besides, Marian is vacationing by the sea. Tessa just spoke to her yesterday.

When the truth of what has happened to Marian reveals itself, Tessa will be forced to choose: between her ideals and her family, between bystanderism and action. Walking an increasingly perilous road, she fears nothing more than endangering the one person she loves more fiercely than her sister: her infant son.

A riveting and exquisite novel about family, terror, motherhood, betrayal, and the staggering human costs of an intractable conflict, Northern Spy cements Flynn Berry's status as one of the most sophisticated and accomplished authors of crime and suspense novels working today.

2022 (Summer)

The Power

Naomi Alderman

In The Power the world is a recognizable place: There's a rich Nigerian boy who lounges around the family pool; a foster kid whose religious parents hide their true nature; an ambitious American politician; and a tough London girl from a tricky family. But then a vital new force takes root and flourishes, causing their lives to converge with devastating effect. Teenage girls now have immense physical power: They can cause agonizing pain and even death. With this small twist of nature, the world drastically resets.

Why We’re Polarized

Ezra Klein

Discover how American politics became a toxic system, why we participate in it, and what it means for our future--from journalist, political commentator, and cofounder of Vox, Ezra Klein.

After Election Day 2016, both supporters and opponents of the soon-to-be president hailed his victory as a historically unprecedented event. Most Americans could agree that no candidate like Donald Trump had ever been elected President before. But political journalist Ezra Klein makes the case that the 2016 election wasn't surprising at all. In fact, Trump's electoral victory followed the exact same template as previous elections, by capturing a nearly identical percentage of voter demographics as previous Republican candidates.

Over the past 50 years in America, our partisan identities have merged with our racial, religious, geographic, ideological, and cultural identities. Those merged identities have attained a weight that is breaking much in our politics and tearing at the bonds that hold this country together.

In this groundbreaking book, Klein shows how and why American politics polarized around identity in the 20th century, and what that polarization did to the way we see the world and each other. And he traces the feedback loops between our polarized political identities and our polarized political institutions that are driving our political system towards crisis.

Neither a polemic nor a lament, Klein offers a clear framework for understanding everything from Trump's rise to the Democratic Party's leftward shift to the politicization of everyday culture. A revelatory book that will change how you look at politics, and perhaps at yourself.

The Lincoln HIghway

Amor Towles

The bestselling author of A Gentleman in Moscow and Rules of Civility and master of absorbing, sophisticated fiction returns with a stylish and propulsive novel set in 1950s America

In June, 1954, eighteen-year-old Emmett Watson is driven home to Nebraska by the warden of the work farm where he has just served a year for involuntary manslaughter. His mother long gone, his father recently deceased, and the family farm foreclosed upon by the bank, Emmett’s intention is to pick up his eight-year-old brother and head west where they can start their lives anew. But when the warden drives away, Emmett discovers that two friends from the work farm have hidden themselves in the trunk of the warden’s car. Together, they have hatched an altogether different plan for Emmett’s future.

Spanning just ten days and told from multiple points of view, Towles’s third novel will satisfy fans of his multi-layered literary styling while providing them an array of new and richly imagined settings, characters, and themes.

The Ministry for the Future

Kim Stanley Robinson

Established in 2025, the purpose of the new organization was simple: To advocate for the world's future generations and to protect all living creatures, present and future. It soon became known as the Ministry for the Future, and this is its story.

From legendary science fiction author Kim Stanley Robinson comes a vision of climate change unlike any ever imagined.

Told entirely through fictional eye-witness accounts, The Ministry for the Future is a masterpiece of the imagination, the story of how climate change will affect us all over the decades to come.

Its setting is not a desolate, post-apocalyptic world, but a future that is almost upon us—and in which we might just overcome the extraordinary challenges we face.

It is a novel both immediate and impactful, desperate and hopeful in equal measure, and it is one of the most powerful and original books on climate change ever written.

How the World Really Works

Vaclav Smil

This is his magnum opus . It distils his over 40 academic books into one peerlessly authoritative yet accessible masterpiece

2021 (Holiday)

A Thousand Brains: A New Theory of Intelligence

Jeff Hawkins

An author, neuroscientist, and computer engineer unveils a theory of intelligence, of understanding the brain and the future of AI. For all of neuroscience's advances, we've made little progress on its biggest question: How do simple cells in the brain create intelligence? Jeff Hawkins and his team discovered that the brain uses maplike structures to build a model of the world-not just one model, but hundreds of thousands of models of everything we know. This discovery allows Hawkins to answer important questions about how we perceive the world, why we have a sense of self, and the origin of high-level thought. 

The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race

Walter Isaacson

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

Klara and the Sun

Kazuo Ishiguro

From her place in the store, Klara, an Artificial Friend with outstanding observational qualities, watches carefully the behavior of those who come in to browse, and of those who pass on the street outside. She remains hopeful that a customer will soon choose her, but when the possibility emerges that her circumstances may change forever, Klara is warned not to invest too much in the promises of humans.

In Klara and the Sun, Kazuo Ishiguro looks at our rapidly changing modern world through the eyes of an unforgettable narrator to explore a fundamental question: what does it mean to love?

Hamnet

Maggie O'Farrell

Drawing on Maggie O'Farrell's long-term fascination with the little-known story behind Shakespeare's most enigmatic play, Hamnet is a luminous portrait of a marriage, at its heart the loss of a beloved child.

Warwickshire in the 1580s. Agnes is a woman as feared as she is sought after for her unusual gifts. She settles with her husband in Henley street, Stratford, and has three children: a daughter, Susanna, and then twins, Hamnet and Judith. The boy, Hamnet, dies in 1596, aged eleven. Four years or so later, the husband writes a play called Hamlet.

Award-winning author Maggie O'Farrell's new novel breathes full-blooded life into the story of a loss usually consigned to literary footnotes, and provides an unforgettable vindication of Agnes, a woman intriguingly absent from history.

A New York Times Notable Book (2020), Best Book of 2020: Guardian, Financial Times, Literary Hub, and NPR.

Project Hail Mary

Andy Weir

Ryland Grace is the sole survivor on a desperate, last-chance mission—and if he fails, humanity and the earth itself will perish.

Except that right now, he doesn’t know that. He can’t even remember his own name, let alone the nature of his assignment or how to complete it.

All he knows is that he’s been asleep for a very, very long time. And he’s just been awakened to find himself millions of miles from home, with nothing but two corpses for company.

His crewmates dead, his memories fuzzily returning, Ryland realizes that an impossible task now confronts him. Hurtling through space on this tiny ship, it’s up to him to puzzle out an impossible scientific mystery—and conquer an extinction-level threat to our species.

And with the clock ticking down and the nearest human being light-years away, he’s got to do it all alone.

Or does he?

2021 (Summer)

Lights Out: Pride, Delusion, and the Fall of General Electric

Thomas Gryta & Ted Mann

How could General Electric—perhaps America’s most iconic corporation—suffer such a swift and sudden fall from grace?

This is the definitive history of General Electric’s epic decline, as told by the two Wall Street Journal reporters who covered its fall.

Since its founding in 1892, GE has been more than just a corporation. For generations, it was job security, a solidly safe investment, and an elite business education for top managers.

GE electrified America, powering everything from lightbulbs to turbines, and became fully integrated into the American societal mindset as few companies ever had. And after two decades of leadership under legendary CEO Jack Welch, GE entered the twenty-first century as America’s most valuable corporation. Yet, fewer than two decades later, the GE of old was gone.

​Lights Out examines how Welch’s handpicked successor, Jeff Immelt, tried to fix flaws in Welch’s profit machine, while stumbling headlong into mistakes of his own. In the end, GE’s traditional win-at-all-costs driven culture seemed to lose its direction, which ultimately caused the company’s decline on both a personal and organizational scale. ​Lights Out details how one of America’s all-time great companies has been reduced to a cautionary tale for our times.

Under A White Sky: The Nature of the Future

Elizabeth Kolbert

The Pulitzer Prize–winning author of The Sixth Extinction returns to humanity’s transformative impact on the environment, now asking: After doing so much damage, can we change nature, this time to save it?

That man should have dominion “over all the earth, and over every creeping thing that creepeth upon the earth” is a prophecy that has hardened into fact. So pervasive are human impacts on the planet that it’s said we live in a new geological epoch: the Anthropocene.

In Under a White Sky, Elizabeth Kolbert takes a hard look at the new world we are creating. She meets scientists who are trying to preserve the world’s rarest fish, which lives in a single, tiny pool in the middle of the Mojave. She visits a lava field in Iceland, where engineers are turning carbon emissions to stone; an aquarium in Australia, where researchers are trying to develop “super coral” that can survive on a hotter globe; and a lab at Harvard, where physicists are contemplating shooting tiny diamonds into the stratosphere in order to reflect sunlight back to space and cool the earth.

One way to look at human civilization, says Kolbert, is as a ten-thousand-year exercise in defying nature. In The Sixth Extinction, she explored the ways in which our capacity for destruction has reshaped the natural world. Now she examines how the very sorts of interventions that have imperiled our planet are increasingly seen as the only hope for its salvation. By turns inspiring, terrifying, and darkly comic, Under a White Sky is an utterly original examination of the challenges we face.

A Promised Land (The Presidential Memoirs #1)

Barack Obama

A riveting, deeply personal account of history in the making, from the president who inspired us to believe in the power of democracy.

In the stirring, highly anticipated first volume of his presidential memoirs, Barack Obama tells the story of his improbable odyssey from young man searching for his identity to leader of the free world, describing in strikingly personal detail both his political education and the landmark moments of the first term of his historic presidency—a time of dramatic transformation and turmoil.

Obama takes readers on a compelling journey from his earliest political aspirations to the pivotal Iowa caucus victory that demonstrated the power of grassroots activism to the watershed night of November 4, 2008, when he was elected 44th president of the United States, becoming the first African American to hold the nation’s highest office.

Reflecting on the presidency, he offers a unique and thoughtful exploration of both the awesome reach and the limits of presidential power, as well as singular insights into the dynamics of U.S. partisan politics and international diplomacy. Obama brings readers inside the Oval Office and the White House Situation Room, and to Moscow, Cairo, Beijing, and points beyond. We are privy to his thoughts as he assembles his cabinet, wrestles with a global financial crisis, takes the measure of Vladimir Putin, overcomes seemingly insurmountable odds to secure passage of the Affordable Care Act, clashes with generals about U.S. strategy in Afghanistan, tackles Wall Street reform, responds to the devastating Deepwater Horizon blowout, and authorizes Operation Neptune’s Spear, which leads to the death of Osama bin Laden.

A Promised Land is extraordinarily intimate and introspective—the story of one man’s bet with history, the faith of a community organizer tested on the world stage. Obama is candid about the balancing act of running for office as a Black American, bearing the expectations of a generation buoyed by messages of “hope and change,” and meeting the moral challenges of high-stakes decision-making. He is frank about the forces that opposed him at home and abroad, open about how living in the White House affected his wife and daughters, and unafraid to reveal self-doubt and disappointment. Yet he never wavers from his belief that inside the great, ongoing American experiment, progress is always possible.

This beautifully written and powerful book captures Barack Obama’s conviction that democracy is not a gift from on high but something founded on empathy and common understanding and built together, day by day.

The Overstory

Richard Powers

The Overstory is a sweeping, impassioned work of activism and resistance that is also a stunning evocation of - and paean to - the natural world. From the roots to the crown and back to the seeds, Richard Powers’s twelfth novel unfolds in concentric rings of interlocking fables that range from antebellum New York to the late twentieth-century Timber Wars of the Pacific Northwest and beyond. There is a world alongside ours—vast, slow, interconnected, resourceful, magnificently inventive, and almost invisible to us. This is the story of a handful of people who learn how to see that world and who are drawn up into its unfolding catastrophe.

A New York Times Bestseller.

An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives

Matt Richtel

A magnificently reported and soulfully crafted exploration of the human immune system–the key to health and wellness, life and death. An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.

A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.

The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.

For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.

Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.

Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

2020

End of year reading list

The New Jim Crow

Michelle Alexander

In this incisive critique, former litigator-turned-legal-scholar Michelle Alexander provocatively argues that we have not ended racial caste in America: we have simply redesigned it. Alexander shows that, by targeting black men and decimating communities of color, the U.S. criminal justice system functions as a contemporary system of racial control, even as it formally adheres to the principle of color blindness. The New Jim Crow challenges the civil rights community--and all of us--to place mass incarceration at the forefront of a new movement for racial justice in America.

Range

David Epstein

Plenty of experts argue that anyone who wants to develop a skill, play an instrument, or lead their field should start early, focus intensely, and rack up as many hours of deliberate practice as possible. If you dabble or delay, you'll never catch up to the people who got a head start. But a closer look at research on the world's top performers, from professional athletes to Nobel laureates, shows that early specialization is the exception, not the rule.

Provocative, rigorous, and engrossing, Range makes a compelling case for actively cultivating inefficiency. Failing a test is the best way to learn. Frequent quitters end up with the most fulfilling careers. The most impactful inventors cross domains rather than deepening their knowledge in a single area. As experts silo themselves further while computers master more of the skills once reserved for highly focused humans, people who think broadly and embrace diverse experiences and perspectives will increasingly thrive.

The Splendid and the Vile

Erik Larson

In The Splendid and the Vile, Erik Larson shows how Churchill taught the British people "the art of being fearless." It is a story of political brinkmanship, but it's also an intimate domestic drama, set against the backdrop of Churchill's prime-ministerial country home, Chequers; his wartime retreat, Ditchley, where he and his entourage go when the moon is brightest and the bombing threat is highest; and of course 10 Downing Street in London. Drawing on diaries, original archival documents, and once-secret intelligence reports--some released only recently--Larson provides a new lens on London's darkest year through the day-to-day experience of Churchill and his family: his wife, Clementine; their youngest daughter, Mary, who chafes against her parents' wartime protectiveness; their son, Randolph, and his beautiful, unhappy wife, Pamela; Pamela's illicit lover, a dashing American emissary; and the advisers in Churchill's "Secret Circle," to whom he turns in the hardest moments.

The Spy and the Traitor: The Greatest Espionage Story of the Cold War

Ben Macintyre

The celebrated author of A Spy Among Friends and Rogue Heroes returns with his greatest spy story yet, a thrilling Cold War-era tale of Oleg Gordievsky, the Russian whose secret work helped hasten the collapse of the Soviet Union.

Unfolding the delicious three-way gamesmanship between America, Britain, and the Soviet Union, and culminating in the gripping cinematic beat-by-beat of Gordievsky's nail-biting escape from Moscow in 1985, Ben Macintyre's latest may be his best yet. Like the greatest novels of John le Carré, it brings readers deep into a world of treachery and betrayal, where the lines bleed between the personal and the professional, and one man's hatred of communism had the power to change the future of nations.

Breath from Salt: A Deadly Genetic Disease, a New Era in Science, and the Patients and Families Who Changed Medicine Forever

Bijal P. Trivedi

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.

In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.

The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.

From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.

Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.